Adicet Bio: the lupus CAR-T readout racing a 2027 cash runway
Adicet is trying to turn prula-cel from a promising autoimmune CAR-T idea into a pivotal-trial story before its disclosed runway reaches the second half of 2027.
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Abivax (ABVX): the ulcerative-colitis readout that has to carry a EUR 530M runway
ABVX is a readout-gated biotech with positive Phase 3 induction data, a much stronger cash position after the 2025 offering, and one big unresolved question: can obefazimod's maintenance data turn runway into a real ulcerative-colitis franchise?
OpenArbutus (ABUS): the $179M settlement windfall hiding inside a pre-commercial HBV biotech
ABUS is suddenly cash-relevant because of a Moderna/Genevant settlement receivable, but the core company is still a small clinical-stage HBV developer that must prove imdusiran can move beyond Phase 2a signals.
OpenAcumen Pharmaceuticals (ABOS): the Alzheimer readout racing a cash clock
Acumen's sabirnetug story is dominated by one late-2026 ALTITUDE-AD readout, a going-concern warning, and a cash runway that may not reach commercial proof.
OpenAardvark Therapeutics (AARD) Coverage Bootstrap: a paused clinical-stage obesity and PWS biotech
Official-source baseline for Aardvark Therapeutics using SEC submissions, SEC XBRL companyfacts, FY2025 10-K, Q1 FY2026 10-Q, company-filed results releases, clinical-update 8-Ks, prospectus filings, and peer filings.
OpenAscentage Pharma (AAPG) Coverage Bootstrap: commercial-stage oncology biotech with China approvals and global Phase 3 optionality
Official-source baseline for Ascentage Pharma using SEC submissions, FY2025 Form 20-F, SEC companyfacts, company-filed FY2025 results releases, ASCO 2026 update, annual meeting materials, and oncology peer filings.
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